Cardiovascular Tests

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Cardiovascular Tests

SpectraCell’s CardioMetabolic test offers a clinically relevant evaluation to help define risk for atherosclerotic cardiovascular disease (ASCVD), progression toward Type 2 Diabetes, and inflammation. It includes SpectraCell’s Advanced Lipoprotein Particle Profile® Plus (LPP® Plus), which measures lipoprotein size and density; cardiovascular risk stratification; and also includes triglycerides and traditional cholesterol screening. 

Each patient is assigned a CardioMetabolic Risk Assessment, which is an indication of your risk (Low, Moderate or High) for developing cardiovascular disease, including stroke and diabetes. In addition, the Type 2 Diabetes Risk Assessment is an estimate of your risk of developing Type 2 Diabetes. The CardioMetabolic test also includes OmegaCheck®, which measures the ratio of omega-6 to omega-3 fatty acids in one’s blood. The higher the content of omega -3 fatty acids, the lower the risk of a fatal heart attack and other inflammatory conditions.

 

Clinical Applications:

  • Inflammation
  • Diabetes
  • Hypertension
  • Insulin Resistance
  • Dyslipidemia
  • Stroke
  • Congestive heart failure
  • Obesity
  • Osteoporosis
  • Lipoprotein Fractionation
  • Lipoprotein Particle Numbers
  • Total Cholesterol
  • Total LDL Particles
  • Total HDL Particles
  • Triglycerides
  • Lipoprotein (a)
  • Leptin
  • Apolipoprotein A-1
  • Apolipoprotein B
  • hs-CRP
  • Homocysteine
  • Insulin
  • Glucose
  • Hemoglobin A1C
  • C-peptide
  • Adiponectin
  • OmegaCheck®
  • Type 2 Diabetes Assessment
  • Estimated Average Glucose (eAG)
  • Homeostatic Model Assessment of
  • Insulin Resistance (HOMA-IR)
  • CardioMetabolic Risk Assessment

Requirements

Specimen Type: Serum, EDTC Whole Blood, Sodium Fluoride

Container: 1 SST, 1 Purple Top 

Fasting: 9-12 hours required; except for HgbA1c. OmegaCheck - preferred but not required. It is recommended that patients do not take a fatty acid supplement within 12-24 hours of collection.
 

Collection

For Serum Tests (SST)

  1. Let SST clot for 20- 30 min. 
  2. Centrifuge within 1 hour of collection for 15 min. At 3000 rpm; do not pour off. 
  3. Label tube with patient name, DOB, and date of collection. 
  4. Ship with the frozen ice pack in the kit provided; keep refrigerated until shipped. 

 

HgbA1c (Purple Top)

  1. Gently invert 5-6 times.
  2. Do not centrifuge.
  3. Label tube with patient name, DOB, and date of collection. 
  4. Ship with the frozen ice pack in the kit provided; keep refrigerated until shipped. 

 

OmegaCheck (Purple Top)

  1. Gently invert 5-6 times
  2. Do not centrifuge
  3. Label tube with patient name, DOB, and date of collection. 
  4. Ship with the frozen ice pack in the kit provided; keep refrigerated until shipped. 

Turnaround Time: 7-10 days

CardioMetabolic Test

Cardiovascular

Healthcare providers licensed in their state may order laboratory testing. 

Order Now

Additional Resources


CardioMetabolic Sample Report

The Pre-Diabetes Biomarkers identify metabolic abnormalities that may progress into diabetes.  Pre-diabetes is a condition where the body cannot efficiently metabolize foods, especially carbohydrates, resulting in impaired glycemic (blood sugar) control which may progress to diabetes when not properly treated or addressed through lifestyle changes.

SpectraCell’s Type 2 Diabetes Risk Assessment is an evaluation of specific risk factors that can indicate the presence of Pre-Diabetes and provide an assessment of a person’s risk for developing Type 2 Diabetes (Low, Moderate, or High). This test can be especially useful for identifying people within higher risk groups that are most likely to benefit from early medical and/ or lifestyle intervention. Other factors that significantly affect a pre-diabetic risk but that are not included in this report include: weight, blood pressure, smoking, inflammation, and family history. 

  • Insulin
  • Glucose
  • Hemoglobin A1C
  • C-peptide
  • Adiponectin
  • Leptin
  • hs-CRP
  • Triglycerides
  • Total HDL Particles

For Serum Tests (SST)

  1. Let SST clot for 20- 30 min. 
  2. Centrifuge within 1 hour of collection for 15 min. At 3000 rpm; do not pour off. 
  3. Label tube with patient name, DOB, and date of collection. 
  4. Ship with the frozen ice pack in the kit provided; keep refrigerated until shipped. 

HgbA1c (Purple Top)

  1. Gently invert 5-6 times.
  2. Do not centrifuge.
  3. Label tube with patient name, DOB, and date of collection. 
  4. Ship with the frozen ice pack in the kit provided; keep refrigerated until shipped.

Pre-diabetes

Cardiovascular

Healthcare providers licensed in their state may order laboratory testing. 

Order Now

Cholesterol has historically been used as the standard indicator for cardiovascular disease, often being classified as “good” (HDL) or “bad” (LDL). Studies have found that it is actually the lipoprotein particles that carry the cholesterol throughout the blood, not the cholesterol within them, that are responsible for key steps in plaque formation and the development of cardiovascular disease. The small, dense, cholesterol-depleted particles impart the highest risk, as does a higher number of these lipoproteins. Standard cholesterol testing does not tell us enough about the particle types – or subgroups – of each of these LDL and HDL families;  therefore, it misses the earliest opportunity to prevent adverse cardiovascular events, when it’s easiest to treat.

Why is it important to know lipoprotein numbers?

Cardiovascular risk increases with a higher LDL particle count. With a higher non-HDL count, the probability of particle penetration of the arterial walls rises, regardless of the total amount of cholesterol contained in each particle. 

More than 30% of the population has cholesterol-depleted LDL, a condition in which a patient's cholesterol may be "normal" but their lipoprotein particle number, and hence their actual risk, could be much higher than expected. This is especially common in people whose triglycerides are high or HDL is low. In the population with a cholesterol-depleted LDL, there can be up to a 40% error in risk assessment. 

LPP® Plus Profile

  • Lipoprotein Fractionation
  • Lipoprotein Particle Numbers
  • Total Cholesterol
  • Total LDL Particles
  • Total HDL Particles
  • Triglycerides
  • Lipoprotein (a)
  • hs-CRP
  • Homocysteine
  • Apolipoprotein A-1
  • Apolipoprotein B
  • Insulin

LPP® Basic Profile

  • Lipoprotein Fractionation
  • Lipoprotein Particle Numbers
  • Total Cholesterol
  • Total LDL Particles
  • Total HDL Particles
  • Triglycerides
  • Lipoprotein (a)

Requirements

Specimen Type: Serum

Container: 1 SST

Fasting: 9-12 hours required

Collection: 

  1. Let SST clot for 20- 30 min. 
  2. Centrifuge within 1 hour of collection for 15 min. At 3000 rpm; do not pour off. 
  3. Label tube with patient name, DOB, and date of collection. 
  4. Ship with the frozen ice pack in the kit provided; keep refrigerated until shipped. 

Expected Turnaround Time: 7-10 business days
We are experiencing a delay in testing and are working to release results as quickly as possible.

Lipoprotein Particle Profile

Cardiovascular

Healthcare providers licensed in their state may order laboratory testing. 

Order Now

Additional Resources


LPP Plus Sample Report
LPP Basic Sample Report